Dr (α) Jekyl and Mister (β) Hyde: often protein varies.
From outside ! Dr (α) Jekyl and Mister (β) Hyde. NusG homologs regulate transcription and coupled processes in all living organisms. The Escherichia coli (E. coli) two-domain paralogs NusG and RfaH have been shown in a recent Cell paper to bear identical N-terminal domains (NTDs) but dramatically different carboxy-terminal domains (CTDs), a β barrel in NusG and an α hairpin in RfaH.
A la découverte de la symbiose et du microbiome dans les rues de Lyon et Villeurbanne
Modeling an ancestral regulation mode of bacterial promoters by DNA supercoiling
The basal mechanism described in this paper affects a wide range of species, and has been tested by extensive analysis of global high-throughput expression data.Altogether, these results confirm and provide a quantitative framework for the long-proposed notion that the discriminator sequence is a significant determinant of promoter supercoiling sensitivity.
Welcome to the High Pressure Biosciences and Biotechnology Conference 2021
The M2E team is under High Pressure